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Amarillo is considered a Medium City with a population of 206,072 and 22,785 businesses. 251 in 2018 were added to the Amarillo Chamber of Commerce business directory which was less than 2017 which had 252.

The economy of Amarillo employs 138,686 people and has an unemployment rate of 4.2%. Some of the largest industries in Amarillo are Professional Services (2,341),Restaurants (681), and Entertainment Agencies & Bureaus (611).
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