Thomasville is considered a Large Town with a population of 26,615 and 3,472 businesses. 27 in 2018 were added to the Thomasville Chamber of Commerce business directory which was more than 2017 which had 25.

The economy of Thomasville employs 16,581 people and has an unemployment rate of 10%. Some of the largest industries in Thomasville are Professional Services (214),Restaurants (103), and Builders & Contractors (95).