San Diego is considered a Megalopolis with a population of 3,210,314 and 126,594 businesses. 2,361 in 2018 were added to the San Diego Chamber of Commerce business directory which was more than 2017 which had 1,729.

The economy of San Diego employs 2,170,172 people and has an unemployment rate of 7%. Some of the largest industries in San Diego are Professional Services (7,759),Restaurants (4,191), and Personal Services & Consultants (3,539).