Demopolis is considered a Small Town with a population of 5,907 and 1,094 businesses. 3 in 2018 were added to the Demopolis Chamber of Commerce business directory which was less than 2017 which had 6.

The economy of Demopolis employs 3,036 people and has an unemployment rate of 12%. Some of the largest industries in Demopolis are Professional Services (108),Restaurants (43), and Government Offices City & Village & Borough (37).